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1

Multiple-dose pharmacokinetics of a long half-life drug: contributions of mathematical modeling

J. R. Nedelman, E. Gibiansky, J. Cramer, J. Kovarik, J. Meligeni, B. Robbins

Journal:

European Journal of Drug Metabolism and Pharmacokinetics

Year:

1997

Language:

english

File:

PDF, 596 KB

english, 1997

2

Facilitating pharmacometric workflow with the metrumrg package for R

Bergsma, Timothy T., Knebel, William, Fisher, Jeannine, Gillespie, William R., Riggs, Matthew M., Gibiansky, Leonid, Gastonguay, Marc R.

Journal:

Computer Methods and Programs in Biomedicine

Year:

2013

Language:

english

File:

PDF, 895 KB

english, 2013

3

Effective mechanical and transport properties of cellular solids

S. Torquato, L.V. Gibiansky, M.J. Silva, L.J. Gibson

Journal:

International Journal of Mechanical Sciences

Year:

1998

Language:

english

File:

PDF, 783 KB

english, 1998

4

A complete characterization of the possible bulk and shear moduli of planar polycrystals

M. Avellaneda, A.V. Cherkaev, L.V. Gibiansky, G.W. Milton, M. Rudelson

Journal:

Journal of the Mechanics and Physics of Solids

Year:

1996

Language:

english

File:

PDF, 2.17 MB

english, 1996

5

Target-mediated drug disposition model: approximations, identifiability of model parameters and applications to the population pharmacokinetic–pharmacodynamic modeling of biologics

Gibiansky, Leonid, Gibiansky, Ekaterina

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Year:

2009

Language:

english

File:

PDF, 587 KB

english, 2009

6

Approximations of the target-mediated drug disposition model and identifiability of model parameters

Leonid Gibiansky, Ekaterina Gibiansky, Tarundeep Kakkar, Peiming Ma

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

2008

Language:

english

File:

PDF, 1.30 MB

english, 2008

7

Applying Bailer's Method for AUC Confidence Intervals to Sparse Sampling

Jerry R. Nedelman, Ekaterina Gibiansky, David T. W. Lau

Journal:

Pharmaceutical Research

Year:

1995

File:

PDF, 803 KB

1995

8

Model-based pharmacokinetic analysis of elotuzumab in patients with relapsed/refractory multiple myeloma

Gibiansky, Leonid, Passey, Chaitali, Roy, Amit, Bello, Akintunde, Gupta, Manish

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

2016

Language:

english

File:

PDF, 916 KB

english, 2016

9

Bounds on the effective moduli of cracked materials

L.V. Gibiansky, S. Torquato

Journal:

Journal of the Mechanics and Physics of Solids

Year:

1996

Language:

english

File:

PDF, 623 KB

english, 1996

10

Multiphase composites with extremal bulk modulus

Leonid V. Gibiansky, Ole Sigmund

Journal:

Journal of the Mechanics and Physics of Solids

Year:

2000

Language:

english

File:

PDF, 3.71 MB

english, 2000

11

Rigorous Link between the Conductivity and Elastic Moduli of Fibre-Reinforced Composite Materials

Gibiansky, L. V., Torquato, S.

Journal:

Philosophical Transactions Mathematical Physical & Engineering Sciences

Year:

1995

Language:

english

File:

PDF, 3.33 MB

english, 1995

12

Psl trails guide exploration and microcolony formation in Pseudomonas aeruginosa biofilms

Zhao, Kun, Tseng, Boo Shan, Beckerman, Bernard, Jin, Fan, Gibiansky, Maxsim L., Harrison, Joe J., Luijten, Erik, Parsek, Matthew R., Wong, Gerard C. L.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.33 MB

english, 2013

13

Investigating Clinically Adequate Concentrations of Oseltamivir Carboxylate in End-Stage Renal Disease Patients Undergoing Hemodialysis Using a Population Pharmacokinetic Approach

Kamal, Mohamed A., Lien, Kayla Yi Ting, Robson, Richard, Subramoney, Vishak, Clinch, Barry, Rayner, Craig R., Gibiansky, Leonid

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2015

Language:

english

File:

PDF, 2.37 MB

english, 2015

14

Thermal expansion of isotropic multiphase composites and polycrystals

L.V. Gibiansky, S. Torquato

Journal:

Journal of the Mechanics and Physics of Solids

Year:

1997

Language:

english

File:

PDF, 1.73 MB

english, 1997

15

On the effective viscoelastic moduli of two-phase media. III. Rigorous bounds on the complex shear modulus in two dimensions

Gibiansky, L. V., Milton, G. W., Berryman, J. G.

Journal:

Proceedings Mathematical Physical & Engineering Sciences

Year:

1999

Language:

english

File:

PDF, 465 KB

english, 1999

16

Effective energy of nonlinear elastic and conducting composites: Approximations and cross-property bounds

Gibiansky, Leonid, Torquato, Salvatore

Journal:

Journal of Applied Physics

Year:

1998

Language:

english

File:

PDF, 417 KB

english, 1998

17

Mathematical description of drug–target interactions: application to biologics that bind to targets with two binding sites

Gibiansky, Leonid, Gibiansky, Ekaterina

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

2017

Language:

english

File:

PDF, 1.28 MB

english, 2017

18

Application of a Two-Analyte Integrated Population Pharmacokinetic Model to Evaluate the Impact of Intrinsic and Extrinsic Factors on the Pharmacokinetics of Polatuzumab Vedotin in Patients with Non-Hodgkin Lymphoma

Lu, Dan, Lu, Tong, Shi, Rong, Gibiansky, Leonid, Agarwal, Priya, Shemesh, Colby S., Dere, Randall C., Ogbu, Uzor, Hirata, Jamie, Chanu, Pascal, Girish, Sandhya, Jin, Jin Yan, Li, Chunze, Miles, Dale

Journal:

Pharmaceutical Research

Year:

2020

File:

PDF, 445 KB

2020

19

Bounds on the complex bulk and shear moduli of a two-dimensional two-phase viscoelastic composite

L.V. Gibiansky, R. Lakes

Journal:

Mechanics of Materials

Year:

1997

Language:

english

File:

PDF, 1.23 MB

english, 1997

20

Optimal design of 1-3 composite piezoelectrics

L. V. Gibiansky, S. Torquato

Journal:

Structural and Multidisciplinary Optimization

Year:

1997

Language:

english

File:

PDF, 564 KB

english, 1997

21

Target-mediated drug disposition model and its approximations for antibody–drug conjugates

Gibiansky, Leonid, Gibiansky, Ekaterina

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

2014

Language:

english

File:

PDF, 666 KB

english, 2014

22

Methods to detect non-compliance and reduce its impact on population PK parameter estimates

Gibiansky, Leonid, Gibiansky, Ekaterina, Cosson, Valerie, Frey, Nicolas, Stark, Franziska Schaedeli

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

2014

Language:

english

File:

PDF, 673 KB

english, 2014

23

Exposure–response analysis of venetoclax in combination with rituximab in patients with relapsed or refractory chronic lymphocytic leukemia: pooled results from a phase 1b study and the phase 3 MURANO study

Deng, Rong, Gibiansky, Leonid, Lu, Tong, Li, Xiaobin, Lu, Dan, Li, Chunze, Girish, Sandhya, Wang, Jue, Boyer, Michelle, Shankar, Noopur, Humphrey, Kathryn, Freise, Kevin J., Salem, Ahmed Hamed, Seymou

Journal:

Leukemia and Lymphoma

Year:

2019

Language:

english

File:

PDF, 1.48 MB

english, 2019

24

Exposure-safety and exposure-efficacy analyses of polatuzumab vedotin in patients with relapsed or refractory diffuse large B-cell lymphoma

Lu, Tong, Gibiansky, Leonid, Li, Xiaobin, Li, Chunze, Shi, Rong, Agarwal, Priya, Hirata, Jamie, Miles, Dale, Chanu, Pascal, Girish, Sandhya, Jin, Jin Yan, Lu, Dan

Journal:

Leukemia and Lymphoma

Year:

2020

File:

PDF, 1.39 MB

2020

25

Performance of Bailer's Method for AUC Confidence Intervals from Sparse Non-Normally Distributed Drug Concentrations in Toxicokinetic Studies

Sudhakar M. Pai, Jerry R. Nedelman, Gerald Hajian, Ekaterina Gibiansky, Vijay K. Batra

Journal:

Pharmaceutical Research

Year:

1996

File:

PDF, 341 KB

1996

26

Assessing drug exposure in rodent toxicity studies without satellite animals

Jerry R. Nedelman, Ekaterina Gibiansky, Francis L. S. Tse, Christine Babiuk

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

1993

Language:

english

File:

PDF, 538 KB

english, 1993

27

Population pharmacodynamic modeling of various extended-release formulations of methylphenidate in children with attention deficit hyperactivity disorder via meta-analysis

Holly Kimko, Ekaterina Gibiansky, Leonid Gibiansky, H. Lynn Starr, Joris Berwaerts, Joseph Massarella, Frank Wiegand

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

2012

Language:

english

File:

PDF, 480 KB

english, 2012

28

Bacteria use type-IV pili to slingshot on surfaces

Fan Jin, Jacinta C. Conrad, Maxsim L. Gibiansky and Gerard C. L. Wong

Journal:

Proceedings of the National Academy of Sciences

Year:

2011

Language:

english

File:

PDF, 1.09 MB

english, 2011

29

Population Pharmacokinetic Analysis of Delamanid in Patients with Pulmonary Multi-Drug Resistant Tuberculosis

Wang, Xiaofeng, Mallikaarjun, Suresh, Gibiansky, Ekaterina

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2020

File:

PDF, 1.14 MB

2020

30

PI-83Model-based design of AQUAVAN® injection dose ranging Phase II study

GIBIANSKY, E, GIBIANSKY, L, WANG, C

Journal:

Clinical Pharmacology & Therapeutics

Year:

2006

Language:

english

File:

PDF, 47 KB

english, 2006

31

Linking interleukin-6 receptor blockade with tocilizumab and its hematological effects using a modeling approach

Leonid Gibiansky, Nicolas Frey

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

2012

Language:

english

File:

PDF, 480 KB

english, 2012

32

Rigorous connection between physical properties of porous rocks

Gibiansky, Leonid, Torquato, Salvatore

Journal:

Journal of Geophysical Research

Year:

1998

Language:

english

File:

PDF, 1.41 MB

english, 1998

33

Rigorous Link between the Conductivity and Elastic Moduli of Fibre-Reinforced Composite Materials

L. V. Gibiansky and S. Torquato

Journal:

Philosophical Transactions of the Royal Society Physical and Engineering Sciences (1990-1995)

Year:

1995

Language:

english

File:

PDF, 707 KB

english, 1995

34

Comparison of Nonmem 7.2 estimation methods and parallel processing efficiency on a target-mediated drug disposition model

Leonid Gibiansky, Ekaterina Gibiansky, Robert Bauer

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

2012

Language:

english

File:

PDF, 576 KB

english, 2012

35

Target-mediated drug disposition model: relationships with indirect response models and application to population PK–PD analysis

Leonid Gibiansky, Ekaterina Gibiansky

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

2009

Language:

english

File:

PDF, 2.16 MB

english, 2009

36

Bounds on the complex bulk modulus of a two-phase viscoelastic composite with arbitrary volume fractions of the components

L.V. Gibiansky, R. Lakes

Journal:

Mechanics of Materials

Year:

1993

Language:

english

File:

PDF, 1.04 MB

english, 1993

37

Three-scale asymptotics for a diffusion problem coupled with the wave equation

Gibiansky, E., Maz'ya, V., Movchan, A.

Journal:

Applicable Analysis

Year:

2005

Language:

english

File:

PDF, 2.39 MB

english, 2005

38

Fospropofol Assay Issues and Impact on Pharmacokinetic and Pharmacodynamic Evaluation

Shah, Ajit, Mistry, Bipin, Gibiansky, Ekaterina, Gibiansky, Leonid

Journal:

Anesthesia & Analgesia

Year:

2009

Language:

english

File:

PDF, 66 KB

english, 2009

39

INFERRING SYSTEMIC EXPOSURE FROM A PHARMACOKINETIC SCREEN: MODEL-FREE AND MODEL-BASED APPROACHES

Jerry R. Nedelman, Adel H. Karara, Cheng-Tao Chang, Ekaterina Gibiansky, Scott McDonald, William T. Robinson

Journal:

Statistics in Medicine

Year:

1995

Language:

english

File:

PDF, 739 KB

english, 1995

40

Population Pharmacokinetic Analysis of Denosumab in Patients with Bone Metastases from Solid Tumours

Leonid Gibiansky, Liviawati Sutjandra, Sameer Doshi, Jenny Zheng, Winnie Sohn, Mark C. Peterson, Graham R. Jang, Andrew T. Chow, Dr Juan José Pérez-Ruixo

Journal:

Clinical Pharmacokinetics

Year:

2012

Language:

english

File:

PDF, 1.31 MB

english, 2012

41

On the Effective Viscoelastic Moduli of Two-Phase Media. I. Rigorous Bounds on the Complex Bulk Modulus

Gibiansky, L. V., Milton, G. W.

Journal:

Proceedings Mathematical Physical & Engineering Sciences

Year:

1993

Language:

english

File:

PDF, 698 KB

english, 1993

42

Population pharmacokinetic model of sedative doses of GPI15715 and propofol liberated from GPI15715

GIBIANSKY, E, GIBIANSKY, L, ENRIQUEZ, J

Journal:

Clinical Pharmacology & Therapeutics

Year:

2005

Language:

english

File:

PDF, 49 KB

english, 2005

43

Pharmacokinetic and Pharmacodynamic Modeling of a Monoclonal Antibody Antagonist of Glucagon Receptor in Maleob/obMice

Yvonne Y. Lau, Peiming Ma, Leonid Gibiansky, Renee Komorowski, Jin Wang, George Wang, Hai Yan, Murielle M. Véniant, Tarundeep Kakkar

Journal:

The AAPS Journal

Year:

2009

Language:

english

File:

PDF, 236 KB

english, 2009

44

Connection between the Conductivity and Bulk Modulus of Isotropic Composite Materials

L. V. Gibiansky and S. Torquato

Journal:

Proceedings Mathematical Physical & Engineering Sciences

Year:

1996

Language:

english

File:

PDF, 725 KB

english, 1996

45

Population Pharmacokinetics of Eltrombopag in Healthy Subjects and Patients With Chronic Idiopathic Thrombocytopenic Purpura

Gibiansky, Ekaterina, Zhang, Jianping, Williams, Daphne, Wang, Zhao, Ouellet, Daniele

Journal:

Journal of Clinical Pharmacology

Year:

2011

Language:

english

File:

PDF, 771 KB

english, 2011

46

An Integrated Assessment of the Effects of Immunogenicity on the Pharmacokinetics, Safety, and Efficacy of Elotuzumab

Passey, Chaitali, Mora, Johanna, Dodge, Robert, Gibiansky, Leonid, Sheng, Jennifer, Roy, Amit, Bello, Akintunde, Gupta, Manish

Journal:

The AAPS Journal

Year:

2017

Language:

english

File:

PDF, 538 KB

english, 2017

47

Asian race and origin have no clinically meaningful effects on polatuzumab vedotin pharmacokinetics in patients with relapsed/refractory B-cell non-Hodgkin lymphoma

Shi, Rong, Lu, Tong, Ku, Grace, Ding, Hao, Saito, Tomohisa, Gibiansky, Leonid, Agarwal, Priya, Li, Xiaobin, Jin, Jin Yan, Girish, Sandhya, Miles, Dale, Li, Chunze, Lu, Dan

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2020

File:

PDF, 800 KB

2020

48

The variance of a better AUC estimator for sparse, destructive sampling in toxicokinetics

Jerry R. Nedelman, Ekaterina Gibiansky

Journal:

Journal of Pharmaceutical Sciences

Year:

1996

Language:

english

File:

PDF, 62 KB

english, 1996

49

Earthquake-like dynamics in Myxococcus xanthus social motility

Gibiansky, M. L., Hu, W., Dahmen, K. A., Shi, W., Wong, G. C. L.

Journal:

Proceedings of the National Academy of Sciences

Year:

2013

Language:

english

File:

PDF, 1.46 MB

english, 2013

50

Double blind, placebo controlled trial of the remission inducing and steroid sparing properties of an ICAM-1 antisense oligodeoxynucleotide, alicaforsen (ISIS 2302), in active steroid dependent Crohn's disease

Yacyshyn, B R, Chey, W Y, Goff, J, Salzberg, B, Baerg, R, Buchman, A L, Tami, J, Yu, R, Gibiansky, E, Shanahan, W R

Journal:

Year:

2002

Language:

english

File:

PDF, 330 KB

english, 2002

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